This gene contains the instructions for making the huntingtin proteinhuntingtin protein The protein produced by the HD gene..

6 min read | A new study suggests that reduced awareness of symptoms, known as anosognosia, may appear even in the earliest ...

In plain language. Written by scientists. ⏱️8 min read | People with Huntington’s disease commonly experience unintended weight loss. A recent article identified the challenges around HD’s impact on ...

Huntington’s disease (HD) involves the loss of cells in the striatum, an area of the brain that plays important roles in movement, cognition, and behaviour. For decades, researchers have been ...

Among the problems faced by people with Huntington’s disease (HD), a common one is weight loss. Many individuals with the disease lose weight over time, even when they are trying to eat enough. This ...

In an update from uniQure, they report that their experimental gene therapy, AMT-130, has the potential to slow Huntington’s disease progression in key clinical study. HD is caused by a faulty copy of ...

Every cell in our body is constantly fixing DNA damage that happens throughout our lifetime. Like a city sending out crews to mend roads and power lines, our cells rely on specialized proteins to keep ...

⏱️ 29 min read | Day 3 of the HD Therapeutics Conference dives into breakthrough science, new tools and bold ideas that are pushing HD research toward better treatments.

Imagine the gene that causes Huntington’s disease (HD) as a vast river. At its source is the CAG repeatCAG repeat The stretch of DNA at the beginning of the HD gene, which contains the sequence CAG ...

⏱️ 9 min read |New research in a HD mouse model points to a key culprit: a small fragment called HTT1a. Lowering HTT1a levels successfully delayed disease signs in mice that model HD, perhaps shaping ...

HSG leadership is kicking things off with a series of intros and brief updates about the meeting agenda and the future of the organization. Stay tuned today as well as Friday and Saturday as we share ...

A BLA, or Biologics Licensing Application, is the formal dossier of information that a company uses to request permission to market a biologic, which is a therapy created from living organisms, like ...