A computational biology-derived compound has shown promise in preclinical models by simultaneously improving levodopa ...

Crown Bioscience has become the ninth member of the Critical Path Institute’s NAMs Developer Coalition, contributing patient-derived xenograft models, tumour organoids and biomarker analysis ...

Engineers at MIT have developed a technique to direct blood vessel growth using mechanical forces, offering a potential ...

A novel epigenetic therapy has demonstrated activity against treatment-resistant acute myeloid leukaemia in preclinical ...

A structure-guided peptide vaccine targeting PCSK9 has demonstrated durable antibody responses and reduced LDL cholesterol ...

A new review finds that next-generation BET-targeted therapies, including selective inhibitors and PROTACs, are addressing ...

In part II of his conversation with Dr Nick Lynch, founder of Curlew Research, Raminderpal Singh asks the uncomfortable ...

A new review examines how advances in drug design, PROTAC degraders and combination therapies are reviving the clinical ...

Ovarian cancer has long proved difficult to treat. Could the answer lie within the disease itself? Discover how synthetic ...

Stanford University researchers have demonstrated that stem cell-derived vascular organoids can regenerate damaged ...

A repurposed small molecule originally developed for spinal cord injury has demonstrated the ability to address multiple ...

Researchers at Cincinnati Children's have demonstrated that AAV-mediated delivery of the human FMR1 gene can restore FMRP ...