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阿尔茨海默病:降低“另一个”关键蛋白,能否延缓认知下降?
编者按:提到阿尔茨海默病大脑中的异常蛋白,很多人首先想到的是β淀粉样蛋白(Aβ)。事实上,Aβ沉积形成的斑块与异常Tau蛋白聚集形成的神经原纤维缠结,是阿尔茨海默病大脑中两类经典的病理特征。长期以来,靶向Aβ一直是阿尔茨海默病新药研发的重要方向。近年 ...
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