Objective To apply large language models (LLMs) to Reddit posts referencing SLE to identify patient-expressed unmet medical ...

Our purpose was to compile information on the haematological manifestations of systemic lupus erythematosus (SLE), namely leucopenia, lymphopenia, thrombocytopenia, autoimmune haemolytic anaemia (AIHA ...

Objective Epidemiological data for primary discoid lupus erythematosus (pDLE) remain limited, particularly for racial/ethnic populations in the USA. The Manhattan Lupus Surveillance Program (MLSP) is ...

Introduction Cognitive symptoms such as ‘brain fog’ are frequent and disabling in patients with SLE. We aimed to develop and ...

Objectives B-cell targeted therapies are increasingly used in systemic lupus erythematosus (SLE). However, real-world evidence on treatment persistence and reasons for discontinuation remains limited.

Objectives To assess hemostatic parameters in SLE patients in relation to disease activity, kidney involvement and presence of extraglomerular vascular changes in kidney biopsies. Methods This ...

Introduction Patients with SLE have an increased risk of infections and infection-related mortality, which may be associated ...

Background Cognitive dysfunction (CD) is highly prevalent in systemic lupus erythematosus (SLE), yet the underlying mechanisms are poorly understood. Neuroimaging utilising advanced MRI metrics may ...

Artificial intelligence and machine learning applications are emerging as transformative technologies in medicine. With greater access to a diverse range of big datasets, researchers are turning to ...

Objective To investigate the role of curcumin in the treatment of lupus nephritis (LN) by inhibiting the migration of neutrophils and the underlying mechanism involved. Methods Two lupus mouse models, ...

Objectives To provide updated long-term safety and efficacy of ICG318 to treat refractory systemic lupus erythematosus (SLE) and lupus nephritis (LN) in a phase I clinical trial. We report up to ...

Objectives Ethnicity and health outcomes are intrinsically interrelated, although mechanisms are complex. SLE is a disease with higher incidence in Asian, Black, Hispanic and Indigenous populations ...