Transferrin-receptor shuttles distribute antibody cargo throughout the parenchyma, steering clear of ARIA-provoking vascular amyloid. Trontinemab is enrolling Phase 3 for early AD, announces plans for ...

As clinicians increasingly make use of amyloid PET, they need to know where to draw the line between amyloid-negative and -positive scans. In the July 13 JAMA, scientists led by Ganna Blazhenets and ...

Microdissection of more than 130 different brain nuclei is performed on frozen brains. These samples are approved for neurochemistry, neuroendocrine, molecular biology, proteomic and genomic studies.

Not a brain bank per se, but a for-pay brain autopsy program. Some brains are kept after autopsy, and tissues from Alzheimer's, other neurological disorders and a few controls, are available to ...

The brain bank houses one of the most extensive collections of human brain tissue in the southern hemisphere, comprising nine different neurological diseases such as Alzheimer’s, Huntington’s, ...

Somewhere, a synapse fires. Sodium and calcium flood the dendrite and trigger transcription of genes necessary for learning and memory. Within minutes, the transport protein Arc reaches the dendrite ...

Turns out, microglia need TDP-43 to properly shape the brain's white matter during development. In the July 8 Nature Neuroscience, scientists led by Rosa Paolicelli at the University of Lausanne, ...

In the quest to understand how APOE4 heightens the risk of Alzheimer’s disease, scientists are drilling down to nuances such as how the variant acts in women versus men, and how it affects cell types.