Gene signatures derived from genomic, transcriptomic, and immune profiling predict prognosis and response to immune ...

Nucleome Therapeutics (‘Nucleome’ or ‘the Company’) – a pioneering biotechnology company unlocking the therapeutic potential of the regulatory genome through its proprietary 3D genomics platform – ...

虽然长链非编码RNA（lncRNAs）在肝细胞癌（HCC）发病机制中发挥关键作用，但调控肝特异性lncRNA的机制仍不明确。在此，研究人员系统分析了分期特异性转录组数据集，以鉴定参与HCC进展的功能相关lncRNA。研究人员鉴定出一种肝特异性lncRNA，命名 虽然长链非编码 ...

Last August, hundreds of scientists hailing from academia and the pharmaceutical industry gathered in Copenhagen for the 12th ...

New study uncovers how SOX4-activated lncRNA disrupts the PUF60-FUBP1 complex to drive c-MYC transcription and tumor ...

Many cancer-associated mutational signatures remain unexplained. Team CAUSE aims to connect DNA damage, mutational patterns, ...

Genome-wide association studies (GWAS) have catalogued hundreds of thousands of genetic variants linked to complex human traits and diseases, with more than 625,000 variant-trait associations across ...

Nadine and David Lipworth have devoted their lives to finding treatment that will restore the daughter they knew.

Clinical genetic testing is now the standard of care for cardiomyopathy, guiding risk stratification, clinical management, and earlier diagnosis in family members. Yet, a large proportion of the ...

This open access article is distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International (CC BY-NC-ND 4.0) license. This work is licensed under a Creative Commons ...

Recent research shows that a father’s health, lifestyle, and environment can influence his children’s development, even before conception. Through sperm epigenetics, factors like diet, stress, toxins, ...