The authors used a combination of super-resolution imaging techniques and liquid pressure flow to fine-tune the stretch ratio of a DNA molecule, improving the lateral resolution of side-by-side ...

In 1869, Swiss scientist Friedrich Miescher isolated a mysterious substance from cell nuclei—an overlooked finding that would later reshape biology and our understanding of life itself. A ...

Thymine modified polymer for delivering DNA into cells. A thymine modified compound, poly (ethylene glycol) (PEG), is bound to DNA through an annealing process, then delivered by intramuscular ...

Most microscopes can only illuminate objects down to a certain size before tiny features blur together. This blurring is known as the diffraction limit of light. Super-resolution imaging techniques, ...

Researchers have demonstrated a novel AI model that can predict which DNA molecules bind with other DNA molecules. A more ...

In a way, sequencing DNA is very simple: There's a molecule, you look at it, and you write down what you find. You'd think it would be easy—and, for any one letter in the sequence, it is. The problem ...

DNA is the molecular basis of heredity, the inherited traits that pass between generations in a person's family tree. Embodied in the sequence of base pairs, DNA carries information between ...

Schematic showing a single DNA duplex bridging two gold electrodes (yellow) patterned on a silicon nitride substrate (green). The setup allows measurement of electrical conductance as metal ions bind ...

Polymerase chain reaction (PCR) is a workhorse for quantifying nucleic acids across a range of applications, including biomanufacturing and clinical research for viral titer, vector copy number, ...

For more than three decades, DNA has been considered the gold standard of forensic science. It has transformed criminal ...